Update: President Infinity 2021 (Congress Infinity 2022 forthcoming) are now macOS compatible. See the blog for the latest https://270soft.com/blog .
Prime Minister Infinity – U.K. and Canada are slated for updates that will include the latest macOSes, but there is no set date at present.
Apple released macOS Catalina on October 7th, 2020. This version of macOS is not compatible with 32-bit apps. The Prime Minister Infinity games are all 32-bit apps.
For Mac users, Prime Minister Infinity games will not work on your Mac until the port is completed, unless you install a virtual machine and then run an older version of macOS on it. ( You can also use your Boot Camp Assistant and then install Windows for free while also having Catalina installed, here. You can also revert back to Mojave if desired. An example of how to revert from Catalina is here.)